Discover the best of you — in only 21 days.
A structured 21-day online program designed by Dr. Sherri Jacobs to engage your body's natural healing abilities. Science-backed, actually quite easy, and genuinely life-changing for those who commit to it.
The CleanUP Metabolic Cleanse is not a crash diet or a deprivation protocol. It's a structured, science-backed program designed to give your body the tools it needs to detoxify naturally, rebalance metabolic function, and set the stage for lasting health.
Designed by Dr. Sherri Jacobs and Dr. Stockton Jacobs, the CleanUP addresses the metabolic foundations that drive most chronic symptoms — from weight gain and fatigue to hormone imbalances and digestive problems.
Participants describe "a clarity of thought, energy and emotion — a clean, light and energized sensation" with measurable gains in health, energy, and overall well-being.
Start Your CleanUPBy targeting the metabolic foundations of health, the CleanUP can help address a wide range of symptoms and conditions that often co-occur and are driven by the same underlying imbalances.
The CleanUP is a fully supported program — you won't be left wondering what to eat or what to do next. Every element is designed to make success as easy as possible.
Engaging sessions on abundance, identifying metabolic saboteurs, and building habits that last beyond the cleanse.
Specific whole-food guidance with the flexibility to choose foods you enjoy within the plan — not a rigid, joyless diet.
Practitioner-grade supplements selected by Dr. Sherri to support detoxification, metabolic function, and cellular repair.
Structured daily practices for metabolic efficiency — sleep hygiene, movement, stress management, and more.
Everything you need in the kitchen — so clean eating feels achievable, not overwhelming.
Practical guidance for reducing your toxic burden at home — environment, products, and lifestyle choices.
Exclusive access to resources, trainings, and support materials throughout the program — available anytime.
A clear roadmap for sustainable eating and habits so you keep the momentum going after Day 21.
Step-by-step protocols Dr. Sherri built to support detox and metabolic health across all 21 days — a proven plan, no guesswork.
"A clarity of thought, energy and emotion… a clean, light and energized sensation that permeates your body and then your life."
"The Metabolic Cleanse is so much more than you can imagine. You gain a sense of being in control of your health and your life."
"They taught me how to listen to and understand my body's cues and then make the right choices."
"I can't explain it. It's like you're no longer along for the ride, or just getting by… with your health or your life."
"The cleanse has been a tremendous experience for both my husband and myself. Not only have we both lost weight, we both feel calmer, focused, and more energetic."
"In two months I have lost 30 pounds, improved all of my pre-cleanse data points, and I don't have afternoon crashes anymore. I HIGHLY recommend this cleanse to anyone looking to improve their lifestyle."
"I have lost 9 pounds and feel great! I never felt hungry and was always satisfied. I don't even want sugary foods anymore. What a great experience!"
"I was traveling the entire time — airports, hotels, restaurants — and still stayed on track for every meal. I lost a solid 5 pounds and kept it off. If I could do it, anyone can!"
"Loved this cleanse! I've loved the break from beer, sugar, and quick-fix processed foods. It's a lifestyle cleanse — I never felt locked in. My cravings are feeling reset."
"I am telling everyone to do the cleanse! I have lost seven pounds and feel great!"
"Big changes! My clothes are getting looser and I can see the difference every morning. I'm sleeping so soundly and have sustainable energy throughout the day. My cravings are gone. I'm feeling energized and beautiful again."
Dr. Sherri walks through the most common questions about the CleanUP Metabolic Cleanse.
Three ways to participate — all include full program access and Dr. Sherri's proven protocols. Dr. Sherri recommends doing the CleanUP seasonally (up to 4× per year) to stay on track.
Go at your own pace with full program access — ideal for returning participants or self-motivated cleansers who want flexible scheduling.
PurchaseBring Dr. Sherri's CleanUP to your workplace, organization, or community. Group pricing and scheduling available — contact us to learn more.
InquireAfter completing your purchase, Dr. Sherri's team will send your member portal login and program start details directly to your email. Questions before you buy? Reach out to Dr. Sherri.
Get started with Dr. Sherri — schedule a consultation or ask about the next CleanUP start date.